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Did you mean bla and brain (2,789 results)?
Genetic and Immunological Characterization of Brain Metastases from Solid Cancers.
Deguchi S, Akiyama Y, Mitsuya K, Ikeya T, Hozumi C, Iizuka A, Miyata H, Maeda C, Ashizawa T, Nagashima T, Urakami K, Ohshima K, Muramatsu K, Sugino T, Ohde Y, Tsubosa Y, Nishimura S, Yamaguchi K. Deguchi S, et al. Anticancer Res. 2024 May;44(5):1983-1994. doi: 10.21873/anticanres.17001. Anticancer Res. 2024. PMID: 38677762
BACKGROUND/AIM: Brain metastasis, a leading cause of cancer death, is a clinical challenge. ...CONCLUSION: High TMB in metastatic lesions indicates potential benefit from immune checkpoint inhibitor usage for brain metastasis and TREML2 and BTLA are factors a …
BACKGROUND/AIM: Brain metastasis, a leading cause of cancer death, is a clinical challenge. ...CONCLUSION: High TMB in metastatic les …
Combination checkpoint therapy with anti-PD-1 and anti-BTLA results in a synergistic therapeutic effect against murine glioblastoma.
Choi J, Medikonda R, Saleh L, Kim T, Pant A, Srivastava S, Kim YH, Jackson C, Tong L, Routkevitch D, Jackson C, Mathios D, Zhao T, Cho H, Brem H, Lim M. Choi J, et al. Oncoimmunology. 2021 Aug 29;10(1):1956142. doi: 10.1080/2162402X.2021.1956142. eCollection 2021. Oncoimmunology. 2021. PMID: 34484870 Free PMC article.
C57BL/6 J mice were implanted with the murine glioma cell line GL261 and randomized into 4 arms: (i) control, (ii) anti-PD-1, (iii) anti-BTLA, and (iv) anti-PD-1 + anti-BTLA. Kaplan-Meier curves were generated for all arms. Flow cytometric analysis of blood and b …
C57BL/6 J mice were implanted with the murine glioma cell line GL261 and randomized into 4 arms: (i) control, (ii) anti-PD-1, (iii) anti- …
Beyond Broca's and Wernicke's: Functional Mapping of Ancillary Language Centers Prior to Brain Tumor Surgery.
Lawrence A, Carvajal M, Ormsby J. Lawrence A, et al. Tomography. 2023 Jun 25;9(4):1254-1275. doi: 10.3390/tomography9040100. Tomography. 2023. PMID: 37489468 Free PMC article. Review.
Functional MRI is a well-established tool used for pre-surgical planning to help the neurosurgeon have a roadmap of critical functional areas that should be avoided, if possible, during surgery to minimize morbidity for patients with brain tumors (though this also has appl …
Functional MRI is a well-established tool used for pre-surgical planning to help the neurosurgeon have a roadmap of critical functional area …
Language Mapping Using Stereo Electroencephalography: A Review and Expert Opinion.
Aron O, Jonas J, Colnat-Coulbois S, Maillard L. Aron O, et al. Front Hum Neurosci. 2021 Mar 10;15:619521. doi: 10.3389/fnhum.2021.619521. eCollection 2021. Front Hum Neurosci. 2021. PMID: 33776668 Free PMC article. Review.
., visual, sensitive, motor, etc.), ECS applied to higher order brain areas determine more subtle behavioral responses. While anterior and posterior language areas in the dorsal language stream seem to share characteristics with primary cortices, basal temporal language ar …
., visual, sensitive, motor, etc.), ECS applied to higher order brain areas determine more subtle behavioral responses. While anterio …
Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets.
Marques RF, Moreno DA, da Silva L, Leal LF, de Paula FE, Santana I, Teixeira G, Saggioro F, Neder L, Junior CA, Mançano B, Reis RM. Marques RF, et al. Front Immunol. 2023 Feb 7;14:1062856. doi: 10.3389/fimmu.2023.1062856. eCollection 2023. Front Immunol. 2023. PMID: 36825029 Free PMC article.
INTRODUCTION: Medulloblastoma is the most common and lethal pediatric malignant brain tumor. It comprises four main molecular subgroups: WNT-activated, SHH-activated, Group 3, and Group 4. ...Cancer immunotherapy targeting immune checkpoints (IC) (PD-1, PD-L1, and CTLA4) h …
INTRODUCTION: Medulloblastoma is the most common and lethal pediatric malignant brain tumor. It comprises four main molecular subgrou …
DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities.
Zhao N, Zhang Z, Wang Q, Li L, Wei Z, Chen H, Zhou M, Liu Z, Su J. Zhao N, et al. EBioMedicine. 2023 Oct;96:104801. doi: 10.1016/j.ebiom.2023.104801. Epub 2023 Sep 17. EBioMedicine. 2023. PMID: 37725855 Free PMC article.
Finally, we proposed and verified that the concomitant triggering of GITR or blockade of BTLA with PD-1 blockade or cisplatin chemotherapy represents effective combination strategies for high-risk locoregional ESCC tumors. ...
Finally, we proposed and verified that the concomitant triggering of GITR or blockade of BTLA with PD-1 blockade or cisplatin chemoth …
Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria.
Lepenies B, Pfeffer K, Hurchla MA, Murphy TL, Murphy KM, Oetzel J, Fleischer B, Jacobs T. Lepenies B, et al. J Immunol. 2007 Sep 15;179(6):4093-100. doi: 10.4049/jimmunol.179.6.4093. J Immunol. 2007. PMID: 17785848
During the course of infection, we found an induction of BTLA in several organs, which was either due to up-regulation of BTLA expression on T cells in the spleen or due to infiltration of BTLA-expressing T cells into the brain. In the brain, we …
During the course of infection, we found an induction of BTLA in several organs, which was either due to up-regulation of BTLA …
Transient aphasias after left hemisphere resective surgery.
Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess CP, Berger MS, Chang EF. Wilson SM, et al. J Neurosurg. 2015 Sep;123(3):581-93. doi: 10.3171/2015.4.JNS141962. Epub 2015 Jun 26. J Neurosurg. 2015. PMID: 26115463 Free PMC article.
Distribution and Network of Basal Temporal Language Areas: A Study of the Combination of Electric Cortical Stimulation and Diffusion Tensor Imaging.
Enatsu R, Kanno A, Ookawa S, Ochi S, Ishiai S, Nagamine T, Mikuni N. Enatsu R, et al. World Neurosurg. 2017 Oct;106:1-8. doi: 10.1016/j.wneu.2017.06.116. Epub 2017 Jun 21. World Neurosurg. 2017. PMID: 28647657
OBJECTIVE: The basal temporal language area (BTLA) is considered to have several functions in language processing; however, its brain network is still unknown. ...The BTLA was located anywhere between 20 mm and 56 mm posterior to the temporal tips. ...
OBJECTIVE: The basal temporal language area (BTLA) is considered to have several functions in language processing; however, its br …
Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease.
Kurnellas MP, Ghosn EE, Schartner JM, Baker J, Rothbard JJ, Negrin RS, Herzenberg LA, Fathman CG, Steinman L, Rothbard JB. Kurnellas MP, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15016-23. doi: 10.1073/pnas.1521206112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621719 Free PMC article.
Analysis of gene expression indicated that the fibrils activated the CD40/B-cell receptor pathway in B-1a cells and induced a set of immune-suppressive cell-surface proteins, including BTLA, IRF4, and Siglec G. Collectively, these data indicate that the fibrils activate B- …
Analysis of gene expression indicated that the fibrils activated the CD40/B-cell receptor pathway in B-1a cells and induced a set of immune- …
19 results